Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or to propylene glycol, sulfites; or to other narcotic pain relievers (e.g., codeine, hydrocodone); or if you have any other allergies.
This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: serious breathing problems (e.g., severe asthma, respiratory depression, hypercarbia), certain bowel diseases (e.g., paralytic ileus), intoxication with medications that depress the nervous system or your breathing (CNS/respiratory depressants such as alcohol or tranquilizers/sedatives).
Before using this medication, tell your doctor or pharmacist your medical history, especially of: brain disorders (e.g., seizures, head injury, increased intracranial pressure), adrenal gland problem (e.g., Addison's disease), difficulty urinating (e.g., enlarged prostate, urethral stricture), personal or family history of regular use/abuse of drugs/alcohol/other substances, kidney or liver disease, heart problems (e.g., low blood pressure, irregular heartbeats), lung diseases (e.g., chronic obstructive pulmonary disease, hypoxia, hypercapnia), metabolic disorders (e.g., low sodium, dehydration), disease of the pancreas (e.g., pancreatitis), psychiatric problems (e.g., major depression, toxic psychosis), spinal problem (kyphoscoliosis), stomach/intestinal problems (e.g., gallbladder disease, severe diarrhea or constipation), underactive thyroid (hypothyroidism).
This drug may make you dizzy or drowsy; do not drive or operate machinery until you know how this medication affects you. Avoid alcoholic beverages.
To minimize dizziness and lightheadedness, get up slowly when rising from a seated or lying position.
Tell your doctor or dentist you are taking this medication prior to having surgery.
Caution is advised when using this drug in the elderly because they may be more sensitive to its side effects (e.g., slow/shallow breathing and drowsiness).
This medication should be used only when clearly needed during pregnancy. It is not recommended for use near or at the time of delivery because of possible side effects in the newborn (e.g., slow/shallow breathing). Discuss the risks and benefits with your doctor. If you have been taking this medication regularly for an extended period of time or in high doses, do not suddenly stop taking it. Consult your doctor for further instructions. Infants born to mothers who have been using this medication, especially for an extended time, may have withdrawal symptoms such as irritability, abnormal/persistent crying, vomiting, or diarrhea. Tell your doctor immediately if you notice any of these symptoms in your newborn.
This medication passes into breast milk and may have undesirable effects on a nursing infant. Breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.